Pazopanib in patients with advanced intermediate-grade or high-grade liposarcoma

Thromboembolism in patients with high-grade glioma.

OBJECTIVE To identify factors related to increased or decreased risk of thromboembolism (TE) in patients with high-grade glioma. DESIGN We performed a retrospective analysis of 64 patients enrolled in two prospective clinical trials of chemotherapy and radiation therapy for newly diagnosed high-grade glioma. MATERIAL AND METHODS The 64 patients were 18 years of age or older and had histolog...

Symptomatic Patients With High-Grade Carotid Stenosis

Background and Purpose The importance of carotid plaque ulceration as a cause of cerebral ischemic symptoms remains uncertain. Moreover, its prominence in symptomatic patients with severe carotid stenosis is unknown. Methods The association between angiographically denned plaque ulceration and risk of subsequent stroke was assessed using Cox proportional hazards regression in 659 patients with ...

Management of Patients with High-grade Glioma

The scientific basis for the surgical management of patients with glioma is rapidly evolving. The infiltrative nature of these cancers precludes a surgical cure, but despite this, cytoreductive surgery remains central to high-quality patient’s care. In addition to tissue sampling for accurate histopathological diagnosis and molecular genetic characterisation, clinical benefit from decompression...

Giant low-grade liposarcoma of distal esophagus.

RapidArc: Initial experience in high grade glioma

Background: Identify the optimal technique of radiotherapy for patients with high grade glioma. Our initial year of experience with RapidArc radiation therapy. Materials and Methods: Planning CT scans of 50 patients with grade IV glioma were reviewed and three plan sets by 3D Conformal Radiotherapy (3DCRT), Intensity Modulated Radiotherapy (IMRT) and Rapid Arc (RA) were generated and the plans ...